Tryptophan is one of the three major amino acid feed additives in the feed market besides tyrosine and methionine. If the supply of L-tryptophan in poultry is insufficient, a series of maladaptive symptoms will appear in the animal's body, such as the slowing down of fat accumulation, slow growth of the body, and dysplasia of testicles in male animals. Moreover, adding a small amount of tryptophan in the feed can achieve the purpose of promoting weight gain of animal body, which has a good effect.
Tryptophan can participate in fat metabolism in the body and reduce the fat content of animal liver, so as to increase the proportion of lean meat in poultry and livestock, and it can also reduce the possibility of aggressive behavior in poultry and livestock. Nicotinamide, which is one of the intermediate metabolites of L-tryptophan, can be made into a feed additive, which can significantly increase the growth rate of poultry, and at the same time can prevent the occurrence of deficiency of nicotinic acid amide in animals. Another metabolic intermediate, serotonin, can promote the production of γ-globulin in animals and enhance the disease resistance of poultry and livestock.
The application of tryptophan in the pharmaceutical industry has always been a research hotspot in the pharmaceutical industry. Tryptophan and its metabolites can be widely involved in the metabolism process in organisms. During the catabolism of tryptophan, a variety of physiologically active substances can be produced, such as serotonin (5-HT), pigments, niacin, indoleacetic acid, alkaloids, coenzymes, melatonin and plant hormones. These metabolites can widely participate in various physiological activities of the human body, and at the same time participate in numerous physiological adjustments.
In recent years, studies have found that tryptophan is not only used to make amino acid injections, but also has good effects on depression, hypertension and pain. It has been widely used in clinical treatment in some European and American countries. Clinical studies have found that the combination of tryptophan, iron preparation and vitamins can enhance their efficacy in the treatment of exercise-induced anemia, and it can also treat digestive ulcers when used with histidine.
The human body cannot synthesize L-tryptophan by itself. In order to meet its own needs, it needs to obtain L-tryptophan from the outside, and the main source is food. Tryptophan essentials play an important role in the metabolism of humans and animals, so tryptophan is also called the second essential amino acid. Thus, tryptophan production plays an important role in the food industry.
People pay more and more attention to the application of tryptophan in food additives. In many places, tryptophan has been used as a food additive, which will have many positive effects on human physiological activities after ingested by the human body. For example, it can improve the body's utilization efficiency of plant protein and accelerate the decomposition and utilization of protein. In addition, tryptophan easily interacts with metal ions. When used as a chelating agent, it is often used as a preservative, added to milk powder to prevent deterioration or used as a fish preservative.
Tryptophan essentials also have certain applications in agricultural pest control. For example, L-tryptophan can make southern caterpillars refuse to eat and thus die. Tryptophan can also be added to salicylic acid and cyclophosphoric acid as a stabilizer to enhance their insecticidal effect. Tryptophan has an indole ring, has good fluorescence absorption, and is the most fluorescent amino acid, so it can be used to detect toxic metal ions in biological ecosystems and natural environments.
Tryptophan is highly sensitive to the environment, and the slight change in polarity of certain substances can also change the absorption spectrum. Therefore, tryptophan can be used as a polarity probe to detect the polarity changes of certain components in the environment.