Beijing Hongvadar Engineering Technology Co.
Beijing Hongvadar Engineering Technology Co.

Feed Additives: Lysine

The chemical name of lysine is 2,6 diaminocaproic acid, and there are two optical isomers, L-form and D-form. Microorganisms produce the L-form. L-Lysine is one of the eight essential amino acids for human and animal nutrition. It plays an important role in regulating the metabolic balance in the body, improving the absorption of cereal protein in the body, improving human dietary nutrition and animal nutrition, and promoting growth and development.


1. The role of lysine


Lysine is one of the essential amino acids for humans and animals. Although vegetable protein contains a small amount of natural lysine supplements, it cannot meet the needs of humans and animals. Adding moderate amounts of lysine to food and animal feed is beneficial for human health and animal growth. At present, the fermentation level of lysine-producing bacteria has reached more than 100g/l, and the microbial fermentation method has become the only method for the industrial production of lysine.


Lysine can meet the needs of animals, promote animal growth, improve amino acid balance, improve feed utilization, and save protein resources. It can improve the nutritional value of plant protein and its feed, and is conducive to the development of protein feed resources. For example, adding restricted amino acids to cake meal feeds can replace fish meal, thereby reducing feed costs and improving meat quality. For example, adding lysine can improve pig carcass quality and increase lean meat rate. Natural lysine supplements are mainly used in pig and poultry feeds in the feed industry, and they are generally added in compound feeds in an amount of 0.1% to 0.3%. A large number of feeding test data show that adding an appropriate amount of lysine to the feed can not only promote the growth of livestock and poultry, but also reduce the amount of crude protein in the feed, thereby reducing the operating cost of the farm and improving economic benefits.


2. Lysine digestibility and utilization


Formulating diets with digestible or available amino acids can improve dietary accuracy and protein utilization efficiency. The absorption efficiency of D-type and L-type lysine is different, D-lysine can hardly be absorbed and utilized, and L-lysine is mainly biologically active. The ε amino group of lysine is very active, and it is easy to combine with the active carbonyl group in the feed to form a complex that is difficult to be absorbed and utilized. Some scholars fed four pigs with terminal ileal fistulas on corn-peanut diets to determine the apparent digestibility of lysine and the requirement of digestible lysine. The results showed that the apparent digestibility of lysine in the basal diet was 79.9%, and the required amount of digestible lysine was 1.03%. When using the comparative slaughtering method to study the utilization of lysine, the deposition of lysine in the carcass was closely related to lysine. There was a linear relationship between acid intake and lysine was 72% efficient for carcass deposition.


3. The nutritional and physiological functions of lysine


Lysine is one of the essential amino acids in animals, and its most important physiological function is to participate in the synthesis of body proteins, which is closely related to animal growth. The main nutritional and physiological functions of lysine are manifested in the following aspects:


(1) It is used in the synthesis of body proteins, and is a component of skeletal muscle enzymes and certain polypeptide hormones.


(2) It is one of the ketogenic and glycogenic amino acids. In the absence of carbohydrates it can be broken down into glucose or ketone bodies.


(3) Under fasting conditions, it is one of the important sources of energy supply.


(4) Participate in fat metabolism. As a precursor of carnitine in lipid metabolism, carnitine is a component of mitochondrial membrane lipases, which allow long-chain fatty acids to pass through the mitochondrial membrane for their oxidation. Therefore, natural lysine supplements are not only an indispensable component for protein synthesis, but also participate in energy metabolism in the body. By adding synthetic lysine to increase the level of lysine in the diet, the growth rate and feed efficiency of animals can be improved. In addition, lysine can also improve the body's ability to resist emergencies.


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