Serotonin is a neurotransmitter produced in animals, and many health problems are linked to levels of serotonin in the brain. Such as irritability, anxiety, fatigue, chronic pain, restlessness, etc. And some individuals may also have unwanted aggression and mood swings. Serotonin is produced from amino acids, and that amino acid is tryptophan. Once an animal is deficient in tryptophan, it is difficult to control emotions. Stress, lack of exercise, lack of sunlight, lack of vitamin B6, B12, vitamin C, folic acid, magnesium, zinc, etc. It can cause a deficiency of tryptophan, which can lead to depression, nervousness, and irritability. Studies have shown that tryptophan is effective in reducing anxiety in animals and humans.
For our pets, anxiety and stress are not just caused by a lack of abundance in life, but also partly genetic. Separation anxiety is 20% to 40% higher among dog behavior problems in the United States and Europe.
There are a number of ways we can address our dog's problems, including training, medication, and complementary therapies. Tryptophan is undoubtedly an important part of complementary therapy. Do you have an idea now? That is to say, whether the dog is happy or not has a certain relationship with the tryptophan in the dog. Unfortunately, this substance cannot be produced on its own and can only be replenished by the outside world.
The related experimental results confirmed that 5-HT is a mediator of stress diarrhea. They analyzed that the possible mechanism of serotonin-induced stress is derived from chromaffin cells and serotonin neurons: 5-HT activates 5-HT3 receptors in the gastrointestinal tract, stimulates the intestinal plexus, and enhances gastrointestinal motility and fluid secretion, causing diarrhea. Some scholars believe that melatonin may be an agonist of serotonin inhibitory neuroreceptors. Some scholars have proposed the melatonin-serotonin system to describe their interaction in the regulation of gastrointestinal motility.
The effect of tryptophan-induced insulin-like growth factor on the development and physiological function of porcine gastrointestinal tract has also attracted much attention. Pig milk in the early stages of colostrum contains high levels of IGFs. Recent studies suggest that the small intestine may be the primary pathway for IGF-1 in the blood. Studies have shown that physiological doses of -1 and -2 can stimulate the proliferation of gastrointestinal cells in newborn piglets, and the small intestine weight, protein and DNA content, and villus height are significantly increased compared with the control group.